"Good Luck, Babe!" is a song recorded by American singer-songwriter Chappell Roan. It was released as a single on April 5, 2024, through Amusement Records and Island Records. She wrote the song along with Justin Tranter and its producer Dan Nigro. A synth-pop track, the lyrics of "Good Luck, Babe!" reference compulsory heterosexuality, describing a woman trying to deny her romantic feelings for Roan and women in general.

"Good Luck, Babe!" received critical acclaim from music critics, who included it on several mid-year rankings of the best songs of 2024. Praised by Billboard as a "well-deserved breakthrough", "Good Luck, Babe!" became Roan's breakout song and a sleeper hit, steadily rising the charts following various live performances including Coachella and The Tonight Show Starring Jimmy Fallon in June 2024. With the track, Roan earned her fastest song to hit 100 million streams on Spotify. "Good Luck, Babe!" became Roan's first top-ten hit, peaking at number six on the Billboard Hot 100. Outside of the United States, "Good Luck, Babe!" topped the charts in Ireland, and peaked within the top ten of the charts in Australia, Canada, Iceland, New Zealand, Singapore, and the United Kingdom, and on the Global 200.