Save Me, San Francisco is the fifth studio album by pop rock band Train (and the first of two albums recorded as a three-piece). It was released on October 26, 2009, through Columbia Records. The album was certified 3× Platinum by the Recording Industry Association of America on February 25, 2024.

The album's first single, "Hey, Soul Sister", which marked a return to the group's folk-rock roots, was released to digital retailers on August 11, 2009. The single has since become Train's fourth career Top 40 hit on the Billboard Hot 100 and second career top 10 hit, reaching number three 26 weeks after it was released. It is also the band's highest-peaking single to date in their native United States, as well as Canada, Australia, the Netherlands and New Zealand.

The follow-up single, "If It's Love", became Train's fourth-career chart-topping single on the Adult Top 40 and peaking at #34 on the Billboard Hot 100. "Marry Me" was released on October 25 as the third single from the record — it debuted on the Billboard Hot 100 at #95 and has reached #34. "Save Me, San Francisco" was released on April 25, 2011, as the fifth single from the record, and peaked at #75 on the Hot 100.