Baby Makin' Music is the thirtieth studio album by the American musical group The Isley Brothers. It was released under the short-lived Def Soul Classics imprint on May 9, 2006. Crediting Ronald Isley as the group's bandleader, it involves production from Gordon Chambers, Jermaine Dupri, Tim & Bob, Ezekiel Lewis, Manuel Seal and R. Kelly.

Their first for the Def Jam-affiliated label, the album peaked at number five on the Billboard 200, while debuting at number one on the Top R&B/Hip-Hop Albums chart. Album sales were helped by the R&B chart success of the first single, "Just Came Here to Chill", and the R. Kelly duet, "Blast Off", which is the only collaboration with Kelly on this album, after he produced their last album, Body Kiss (2003).

Following the album's release, the Isley Brothers ended up on a temporary hiatus following lead singer Ronald Isley's conviction on tax evasion charges, having served three years in federal prison before being released in 2010 and releasing a solo album.