Leprosy is the second studio album by Florida death metal band Death, released on November 16, 1988 by Combat Records.

The album is notable in its different tone and quality from the band's 1987 debut, it is the first example of producer and engineer Scott Burns' work heard on many of the death metal and grindcore albums of that era. The cover is featured in Metal: A Headbanger's Journey. It is the first album to feature drummer Bill Andrews and the only one to feature guitarist Rick Rozz.

In a poll by the German Rock Hard magazine, Leprosy was voted the number one of the 25 most important death metal albums of all time. On April 29, 2014, a three-disc remastered edition containing bonus tracks was released via Relapse Records.

The title track was covered by the blackened death metal band Akercocke on their 2007 album Antichrist. Dutch melodic death metal band Callenish Circle covered "Pull the Plug" as a bonus on their Flesh Power Dominion album, released in 2002; shortly thereafter, Norwegian band Zyklon also recorded "Pull the Plug" to be used as a bonus track. Finnish thrash metal band Mokoma covered the track "Open Casket", with lyrics in Finnish and titled "Avoin Hauta", on their EP Viides Vuodenaika. "Pull the Plug" was also covered by American band Revocation.