Throbbing Gristle were an English music and visual arts group formed in Kingston upon Hull by Genesis P-Orridge and Cosey Fanni Tutti, later joined by Peter "Sleazy" Christopherson and Chris Carter. They are widely regarded as pioneers of industrial music. Evolving from the experimental performance art group COUM Transmissions, Throbbing Gristle made their public debut in October 1976 in the COUM exhibition Prostitution, and released their debut single "United/Zyklon B Zombie" and debut album The Second Annual Report the following year. P-Orridge's lyrics mainly revolved around mysticism, extremist political ideologies, sexuality, dark or underground aspects of society, and idiosyncratic manipulation of language inspired by the techniques of William S. Burroughs.

The band released several subsequent studio and live albums—including D.o.A: The Third and Final Report of Throbbing Gristle (1978), 20 Jazz Funk Greats (1979), and Heathen Earth (1980)—on their own record label Industrial Records, building a reputation with their transgressive and confrontational aesthetics; they included the extensive use of disturbing visual imagery, such as ironic fascist and Nazi symbolism and pornography, as well as that of noise and sound manipulation influenced by the works of Burroughs and Brion Gysin.

Throbbing Gristle dissolved in 1981 due to interpersonal differences; the individual members went on to participate in other projects, such as Psychic TV, Coil, and Chris & Cosey. The band was reformed in 2004, and released three more studio albums—TG Now (2004), Part Two (2007), and The Third Mind Movements (2009)—before disbanding again after P-Orridge's departure in October 2010 and Christopherson's death the following month. The band's final studio project, a cover version of the 1970 Nico album Desertshore entitled The Desertshore Installation, was released in 2012 under the moniker X-TG.