Megurine Luka (巡音ルカ, Megurine Ruka), codenamed "CV03", is a Vocaloid software developed by Crypton Future Media, headquartered in Sapporo, Japan. Its official moe anthropomorphism is a 20-year-old woman. She uses Yamaha Corporation's Vocaloid 2 and Vocaloid 4 singing synthesizer technology. Her voice is sampled from Yū Asakawa. She has performed alongside other Vocaloids at live concerts onstage as an animated hologram projection.

Her official code name, CV03, refers to their position as the third Vocaloid made by Crypton Future Media for their "Character Vocal Series" (abbreviated "CV Series"), succeeding both Hatsune Miku (code-named CV01) and Kagamine Rin/Len (code-named CV02).