Jane Sheldon is a Sydney-born Australian soprano, largely based in New York City. She is an artistic associate at Sydney Chamber Opera.

Eliza Aria from Elena Kats-Chernin's ballet Wild Swans was first recorded by Sheldon in 2004 with the Tasmanian Symphony Orchestra. This recording was used in a series of television and cinema advertisements for British bank Lloyds TSB, and then as the theme music for Phillip Adams' ABC Radio National programme Late Night Live. It was nominated for Best Classical Album at the 2005 ARIA Awards.

In 2018, Sheldon performed in the premiere of Damien Ricketson's wordless opera The Howling Girls, directed by Adena Jacobs at Carriageworks. In 2019, Sydney Chamber Opera presented the work at the Tokyo Festival.

In 2019, she gave the Australian premiere of Kaija Saariaho's La Passion de Simone at Sydney Festival with Sydney Chamber Opera and the Song Company.

Her 2022 album, I am a tree, I am a mouth was listed in The New Yorker's notable performances and recordings of 2022. In 2022 Sheldon was awarded Work of the Year (Dramatic) for composition at the Art Music Awards.