Enrique Mazzola is a Spanish-born Italian conductor. He studied at the Giuseppe Verdi Milan Conservatory.

Renowned as an expert interpreter and champion of bel canto opera and a specialist in French repertoire, Mazzola is in demand worldwide as both an operatic and symphonic conductor.

Between 1999 and 2003, he was the artistic and music director of the Cantiere Internazionale d'Arte in Montepulciano He served as the artistic and music director of the Orchestre national d'Île-de-France from the 2012/13 to 2018/19 season He is nominated as principal guest conductor at Deutsche Oper Berlin from the 2018/19 season As of July 1, 2021, Mazzola is music director of Lyric Opera of Chicago In 2022, he is appointed Conductor in Residence at Bregenz Festival