Alisa Mizuki (観月ありさ, Mizuki Arisa, born December 5, 1976) is a Japanese actress and singer. She began her career as a child model and gained attention for starring in commercials for Fujicolor, among other brands, in the early 1990s.

She released her debut single "Densetsu no Shōjo" in 1991, for which she won the Newcomer Award at the 33rd Japan Record Awards. Mizuki has recorded material penned by Yumi Matsutoya, Anri and Tetsuya Komuro, the latter of whom produced her signature song, "Too Shy Shy Boy!".

Mizuki made her film debut in Reiko, Psyche Resurrected (1991), which garnered her the Japan Academy Film Prize for Newcomer of the Year. As an actress, she is best known for her portrayal of Izumi Asakura in the comedy series Nurse no Oshigoto (1996–2002), which spawned a feature film. She was further nominated for a Japan Academy Film Prize for her lead role in My House (2003).

In 2010, Mizuki set the Guinness World Record for being the leading actress in a television drama series for nineteen consecutive years.