"One Kiss" is a song by Scottish DJ and record producer Calvin Harris and English-Albanian singer Dua Lipa. The song was released for digital download and streaming as a standalone single, through Columbia Records and Sony Music on 6 April 2018. It was later included on Dua Lipa: Complete Edition (2018), the super deluxe reissue of Lipa's eponymous debut studio album, and on Harris' seventh studio album, 96 Months (2024). The song was written by Harris and Lipa alongside Canadian singer Jessie Reyez, with Harris solely handling the production. It is a dance-pop, diva house and tropical house song with 1990s, electro house, Eurodance, funky disco, funk house, psychedelic electropop and UK garage elements. Horns, organs, and a synth-line are featured within the song, as well as house beats. Lyrically, the song is about instantly falling in love with a romantical interest after a kiss.

Music critics praised the throwback sound of "One Kiss" as well as its summertime aesthetic. The song won the Brit Award for British Single of the Year at the 2019 Brit Awards. It appeared on year-end lists by numerous publications including Billboard, The Guardian and Time Out. The song spent eight weeks atop the UK Singles Chart, standing as both's longest running number one single in the country. It further peaked in the same spot of charts in 32 other countries, including Germany, Ireland and the Netherlands. The song has since been certified multi-platinum in 13 countries, including Diamond in France, Mexico, and Poland, as well as a quintuple platinum in the UK. It was the biggest song of 2018 in the UK, as well as in the Netherlands and in the Flanders region of Belgium.

An accompanying music video was directed by Emil Nava and released in May 2018. The video features Lipa in front of a green screen that shows many settings, including a pool where Harris appears as the singer's waiter. The visual received praise from critics, who highlighted the aesthetics and costumes. Harris and Lipa promoted "One Kiss" with several live performances, including ones for The Graham Norton Show, the 61st Annual Grammy Awards, and the 2019 Brit Awards. Several remixes of the song have been released, including ones by Jauz, Oliver Heldens, and R3hab.