Twelve Carat Toothache is the fourth studio album by American singer Post Malone. It was released on June 3, 2022, by Mercury and Republic Records. The album contains 14 tracks and includes guest appearances from Roddy Ricch, Doja Cat, Gunna, Fleet Foxes, the Kid Laroi, and the Weeknd. The deluxe edition was later released on June 7, 2022, including two new tracks, "Waiting For Never" and "Hateful".

Twelve Carat Toothache was supported by three singles: "One Right Now", "Cooped Up", and "I Like You (A Happier Song)". The album received generally positive reviews from critics. It debuted at number two on the US Billboard 200, earning 121,000 album-equivalent units in its first week. The album is Post Malone's fourth top-five album in the US.