Like a Prayer is the fourth studio album by American singer-songwriter Madonna, released on March 21, 1989, by Sire Records. It saw the singer reunited with Patrick Leonard and Stephen Bray, with whom she had collaborated on her previous studio album True Blue (1986), and the soundtrack to the 1987 film Who's That Girl; artist Prince also collaborated on the record, co-writing and co-producing one of the tracks alongside Madonna. Her most introspective release at the time, Like a Prayer is a pop record with elements of rock and dance pop. Its lyrics deal with personal themes she had been too afraid to approach on previous albums: her Catholic upbringing, her troubled marriage to actor Sean Penn, the death of her mother, and her relationship with her father.

Upon its release, Like a Prayer received universal acclaim from music critics, who praised its introspective tone, cohesiveness, and Madonna's increased artistic merit. It was also an international success, reaching the top of the charts in 20 countries, and was certified quadruple platinum in the United States by the Recording Industry Association of America (RIAA). Worldwide, it has sold over 15 million copies. Six singles were released from the album: the title track became Madonna's seventh number one hit on the US Billboard Hot 100, while "Express Yourself" and "Cherish" both peaked at number two, and "Keep It Together" became a top-ten hit.

The album was promoted on Madonna's third concert tour, 1990's Blond Ambition World Tour, which visited cities in Asia, North America, and Europe. In retrospective reviews, Like a Prayer has been noted as a turning point in Madonna's career; she began to be seen as a serious artist rather than a mere pop star. Critics and authors also pointed out influence from the album on the work of modern female singers. Often referred to as one of the greatest albums of all time, Like a Prayer has been included in several musical reference books and best-of lists, including Rolling Stone's 500 Greatest Albums of All Time.