Natalie Laura Mering (born June 11, 1988), known professionally as Weyes Blood (pronounced , like "wise blood"), is an American singer, songwriter, and musician. She was primarily raised in Doylestown, Pennsylvania. She has been performing her own material under variations of the name Weyes Blood since 2003.

Mering's career began with her early involvement in the underground noise music scene and tenure as a member bassist of the Portland, Oregon-based experimental rock group Jackie-O Motherfucker and singer for the band Satanized.

As Weyes Bluhd she released three self-released solo albums exploring softer pop and folk sounds before adopting the alternate moniker Weyes Blood to release The Outside Room (2011) on micro-label Not Not Fun Records. She then signed a recording contract with independent label Mexican Summer, releasing The Innocents (2014) and Front Row Seat to Earth (2016). She released her fourth studio album, Titanic Rising (2019) on Sub Pop, to critical acclaim. Her fifth studio album, And in the Darkness, Hearts Aglow, was released on Sub Pop on November 18, 2022 to further acclaim.