Anne Erin Clark (born September 28, 1982), known professionally as St. Vincent, is an American musician and singer. Her guitar playing has been praised for its melodic style and use of distortion, and she has been listed among the best guitarists of the 21st century by multiple publications. Rolling Stone named Clark the 26th-greatest guitarist of all time in 2023.

Raised in Dallas, St. Vincent began her music career as a member of the Polyphonic Spree. She was also a member of Sufjan Stevens' touring band before forming her own band in 2006. Her debut solo album, Marry Me, was released in 2007; it was followed by Actor (2009) and Strange Mercy (2011). In 2012, St. Vincent released Love This Giant, an album made in collaboration with David Byrne of Talking Heads. Her fourth studio album, St. Vincent (2014), received widespread acclaim from contemporary critics and was named album of the year by Slant Magazine, NME, The Guardian and Entertainment Weekly. She collaborated with producer and songwriter Jack Antonoff for her albums Masseduction (2017) and Daddy's Home (2021) and self-produced her seventh album All Born Screaming (2024).

St. Vincent produced Sleater-Kinney's 2019 album The Center Won't Hold and co-wrote Taylor Swift's Billboard Hot 100 number-one single "Cruel Summer". She also directed a segment in the 2017 anthology horror film XX, and co-wrote and starred in the psychological thriller film The Nowhere Inn (2020).