No Knife was a band from San Diego, California. They played an innovative form of rock that combined aspects of post-punk, post-hardcore, indie rock, and many other genres, influenced by a wide variety of acts, including Pitchfork, Pixies, the Cure, Erik Satie, Steel Pulse, Édith Piaf, and aMiniature. No Knife once won the San Diego Music Award for "Best Punk Rock Band."

The band's original lineup was Mitch Wilson (vocals/guitar), Brian Desjean (bass), Aaron Mancini (guitar/vocals), and Ike Zaremba (drums). Prior to their second full-length, the band replaced Mancini with Ryan Ferguson (guitar/vocals). After their first and second full-lengths, Drunk on the Moon (1996) and Hit Man Dreams (1997), Chris Prescott was enlisted to play drums. The group went on to release two more full-lengths: Fire in the City of Automatons (1999) and Riot for Romance! (2002).

No Knife often toured with Jimmy Eat World. After hinting on their website in March 2008 that they might reunite in late 2008 or early 2009, the band was announced as the opening act for three west coast dates on Jimmy Eat World's "Clarity x 10" tour. No Knife played their final show Thursday, June 18, 2009, at the Belly Up Tavern in Solana Beach, Ca. The last song performed was "Mission Control".

The band reunited to play shows in 2014, 2015, 2019, and 2024 mostly at The Casbah in San Diego. On July 15, 2019, they ended their set with "The Red Bedroom"