Kylesa is an American sludge metal band that was formed in Savannah, Georgia. Their music incorporates experimentalism with heavy riffs, drop-tuned guitars and elements of psychedelic rock. The group was established in 2001 by the former members of Damad, with the addition of guitar player Laura Pleasants who is from North Carolina.

The band has since undergone lineup changes; the remaining original members are Phillip Cope and Laura Pleasants. In 2006, the band added two drummers, Carl McGinley and Jeff Porter. Eric Hernandez joined in 2008 to replace Porter. In April 2016, the band announced that they would be going on an indefinite hiatus. On August 20, 2024 Roadburn Festival announced Kylesa's first reunion show at their 2025 edition, followed by announcements from ArcTanGent Festival in the UK, Inferno Fest in Norway, and A Colossal Weekend in Denmark.