El Cuarteto de Nos (stylized as Cuarteto de Nos) is an Uruguayan rock band formed in 1984 in Montevideo. Over the years, due to its particular sound that mixes elements of hip hop, alternative rock, comedy rock and Latin music, the group has developed an immense amount of popularity and praise in Latin America and Hispanic countries. The band won two Latin Grammy Awards in 2012 for Best Pop/Rock Album and Best Rock Song.

El Cuarteto de Nos has released 16 studio albums since 1984, as well as two compilation albums on numerous record labels, including Ayuí/Tacuabé, Orfeo, Sony BMG, Koala Records, Manzana Verde, Bizarro Records, EMI, and Warner Music. They have experimented with many genres, and are one of the most important and recognized bands from Uruguay and Latin America in general. They've had four lineups with the current one standing since 2024 with the departure of bassist Santiago Tavella.