Calle 13 is a Puerto Rican alternative hip-hop band formed by stepbrothers Residente (lead vocalist, songwriter) and Visitante (multi-instrumentalist, vocalist, beat producer), along with their half-sister iLe, also known as PG-13 (backing vocals).

Pérez and Cabra first were discovered by Elias De Leon. They were subsequently given a record deal with White Lion Records after leaving a demo with A&R Director Carlos "Karly" Rosario. After the song "Querido FBI" was released, the group gained attention in Puerto Rico. In 2005, Calle 13 released its eponymously titled debut album, which included the singles "Se Vale Tó-Tó" and "¡Atrévete-te-te!" and reached number 6 on the Billboard Top Latin Albums chart. In 2007, the group released its second album, Residente o Visitante, which experimented with a wide variety of genres and reached number 1 on the Top Latin Albums chart. The album helped the group gain success throughout Latin America and win three Latin Grammys. The group released its third album, Los de Atrás Vienen Conmigo, in 2008, which won Album of the Year at the 2009 Latin Grammy Awards. Calle 13 released Entren Los Que Quieran in November 2010 and its latest album, Multi Viral, on March 1, 2014.

Calle 13 is noted for its eclectic musical style, often using unconventional instrumentation in its music, which distances the group from the reggaeton genre. The band is also known for its satirical lyrics as well as social commentary about Latin American issues and culture. The stepbrothers are strong supporters of the Puerto Rican independence movement, a stance that has generated controversy. For their work, the group has won twenty-one Latin Grammy Awards, holding the record for the most Latin Grammy wins. They have also won three Grammy Awards.