Luther Tucker (January 20, 1936 – June 18, 1993) was an American blues guitarist.

While soft-spoken and shy, Tucker made his presence known through his unique and clearly recognizable guitar style. Tucker helped to define the music known as Chicago blues, but played everything from blues to soul, rock, jazz and gospel, when given the chance. While never achieving the fame and notoriety of some of his contemporaries, he was considered a great guitarist whether playing his own lead style or playing on the recordings of B.B. King, Mel Brown, Pat Hare, or Elmore James. He is considered one of the most prominent rhythm guitarists of Chicago blues along with Eddie Taylor, Jody Williams and Freddie Robinson. He variously worked with Little Walter, Otis Rush, Muddy Waters, John Lee Hooker, The James Cotton Blues Band and Elvin Bishop.